By Ronald DeMatteo
Even if you are a newly clinically determined GI Stromal sufferer, a survivor, or a pal or relative of both, this publication bargains support. the one textual content to supply the doctor's and patient's perspectives, a hundred Questions & solutions approximately Gastrointestinal Stromal Tumors (GIST) grants authoritative, functional solutions in your questions about therapies, post-treatment caliber of existence, resources of aid, and lots more and plenty extra. This ebook is a useful source for someone dealing with the actual and emotional turmoil of this scary disorder.
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Extra info for 100 Questions & Answers About Gastrointestinal Stromal Tumor(GIST)
Neighboring cells secrete these growth factors. KIT becomes activated by interacting with a specific growth factor called stem cell factor. PDGFRA becomes activated by interacting with a different growth factor called Platelet-Derived Growth Factor (PDGF). As the name implies, PDGF was originally found in platelets and normally plays a role to facilitate healing wounds. The growth factors “awaken” the resting KIT and PDGFRA so that they will transmit growth signals from the outer cell surface into the interior of the cell.
Sometimes a spouse may notice a tumor before the patient does. ” A GIST can also be discovered incidentally on a radiologic test such as a CT scan or an MRI or during an abdominal operation that is performed for some other reason. An endoscopy or colonoscopy may also identify an unsuspected GIST. Fatigue, unintentional weight loss, a change in bowel habits, decreased appetite, and chronic, low-grade fevers may also be evident. These symptoms are not specific for GIST, however, and may occur with other tumors or benign conditions, such as ulcers, diverticulitis, or inflammatory bowel disease.
If they ask you when your treatment will be over, it is okay to tell them that you don’t know. Reassure them that you will keep them informed about any changes. Describe how your disease and treatment will affect them. Explain who will take care of them if you will be in the hospital or if you will be coming home late from a doctor’s visit or treatment. Explain how your disease and treatment will affect their usual routines and activities. Be sure to ask whether they have any worries (for this answer, the authors are grateful to Eileen O’Reilly, MD, and Joanne Frankel Kelving, RN, MSN, authors of 100 Questions & Answers About Pancreatic Cancer).
100 Questions & Answers About Gastrointestinal Stromal Tumor(GIST) by Ronald DeMatteo