By Robert Lev
Adenomatous Polyps of the Colon: Pathobiological and Clinical Features consolidates the giant physique of uncomplicated technological know-how and scientific info linked to adenomatous polyps of the colon, a lot of it encouraged by way of the belief that almost all colorectal carcinomas appear to come up in such polyps. This publication strives to judge those facts, with specific emphasis on their implications for administration of polyp-bearing matters. issues comprehensively explored comprise anatomy and histology of the traditional colon; pathologic features of adenomatous polyps, differential analysis, and grading schemes for measure of dysplasia and villosity; adenomatous polyposes; histologic and epidemiologic facts for the malignant power of adenomatous polyps; and detection and administration, with specified realization to endoscopy, endoscopic polypectomy, the malignant polyp, and post-polypectomy surveillance schedules.
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Additional resources for Adenomatous Polyps of the Colon: Pathobiological and Clinical Features
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Evidence for this includes the presence of mitoses noted histologically and of surface cells labeled by DNA precursors, such as tritiated thymidine, in radioautographs. A similar retention of replicative capacity is found in colorectal cancer cells. , 1985). The expansion of the proliferative compartment to include surface epithelium is also found in morphologically normal epithelium in patients with familial polyposis and, along with increased labeling index, in some normal mucosae adjacent to polyps from nonpolyposis patients (Deschner & Lipkin, 1975).
Pathology Kalus M (1972) Carcinoma and adenomatous polyps of the colon and rectum in biopsy and organ tissue culture. Cancer 30:972-982. Kanemitsu T, Koike A, Yamamoto S (1985) Study of the cell proliferation kinetics in ulcerative colitis, adenomatous polyps and cancer. Cancer 56: 1094-1098. Kaye GI, Pascal RR, Lane N (1971) The colonic pericryptal fibroblast sheath: Replication, migration, and cytodifferentiation of a mesenchymal cell system in adult tissue. III. Replication and differentiation in human hyperplastic and adenomatous polyps.
Adenomatous Polyps of the Colon: Pathobiological and Clinical Features by Robert Lev