By Amar Chatterjee
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1991). Decreased pulse amplitude and frequency in the early follicular phase cause a failure of folliculogenesis and the resulting deficiency of ovarian steroids subsequently leads to loss of the bone mass (Warren, 2011). Estrogen deficiency was proposed as the main factor contributing to low BMD in anorexia nervosa. , 1994). The BMD at the lumbar spine determined by various methods is reduced in adolescent girls with amenorrhea, as compared with those who have regular cycles. , 2000). , 1991).
Diedrich, K. & Griesinger, G. (2010). Ongoing pregnancy after human menopausal gonadotrophin stimulation and timed intercourse in 40 years old women with undetectable Anti-müllerian hormone levels, Fertil Steril 94(4): e71–2. , Klitus, M. & Mintzer, D. (2005). Chemotherapy-induced amenorrhea from adjuvant breast cancer treatment: the effect of the addition of taxanes, Clin. Breast Cancer 6(5): 421–424. , Sertoli, M. & Rosso, R. (1997). Amenorrhea induced by adjuvant chemotherapy in early breast cancer patients: prognostic role and clinical implications, Breast Cancer Res Treat 43: 189–190.
1993). , 2000). 2 Adulthood In 18 anorexic women (mean age: 25 years, ranging from 19 to 36 years) with amenorrhea for at least one year, a lower BMD was detected as compared with the BMD of control group. , 1991). , 1991). , 1991). 4. , 1999). However, the data obtained in the adult anorexic women cannot be extrapolated to the anorexic adolescents where the rate of bone growth and mineral apposition remains active. , 1993). Most studies in adolescents with anorexia nervosa have included a small number of patients and without specific information about the markers of bone turnover, including simultaneous measurements of the bone formation/resorption markers.
Amenorrhea by Amar Chatterjee