By Ashim Datta, Vineet Rakesh
Prepared round challenge fixing, this ebook lightly introduces the reader to computational simulation of biomedical delivery procedures, bridging basic concept with real-world functions. utilizing this e-book the reader will achieve a whole beginning to the topic, beginning with challenge simplification, enforcing it in software program, via to reading the implications, validation, and optimization. Ten case stories, concentrating on rising parts similar to thermal treatment and drug supply, with effortless to keep on with step by step directions, supply ready-to-use templates for additional functions. answer technique utilizing the widely used software COMSOL Multiphysics is defined intimately; precious biomedical estate facts and correlations are integrated; and history idea info is given on the finish of the booklet for simple reference. a mix of brief and prolonged workouts make this ebook an entire path package deal for undergraduate and starting graduate scholars in biomedical and biochemical engineering curricula, in addition to a self-study advisor.
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Additional resources for An Introduction to Modeling of Transport Processes: Applications to Biomedical Systems
It can vary spatially. For example, the initial condition in a drug delivery problem may involve some previous presence of the drug that varies with position. In a heat transfer problem, initially, the material may not be at uniform temperature, but exhibit spatially varying temperatures. 18 Schematic showing two possible ways (either as surface flux or as source term) of implementing radiative energy incident at a surface; depending on the penetration depth of the radiation into the material.
Transient Transient means changing with time, or unsteady. The transient term denotes rate of change of storage. Transient solutions can consume a lot of computer time and also be numerically challenging. Thus it is important to decide whether a transient solution is really necessary. The transient term should be retained when changes over time (during the time period of interest) are likely to be significant and are of interest. 7 Governing equations though achieving steady state is of interest, we may have to start transient and run the program long enough for the process to reach steady state.
Generation (or source) The generation term is also referred to as the source term. Depletion is the negative of generation, also called a sink term. For heat transfer, the generation term represents the contribution from volumetric generation of heat, converted from some other form of energy, as in electromagnetic, ultrasonic or other modes of heating. Metabolic heat generation is another type of heat generation, resulting from biochemical conversion. When such modes of heating or metabolic generation are present, this term needs to be retained in the equation.
An Introduction to Modeling of Transport Processes: Applications to Biomedical Systems by Ashim Datta, Vineet Rakesh