By Minoru Ueda (Ed.)
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16: 413,1997 20. Kang MK, Guo W, Park NH. Replicative senescence of normal human oral keratinocytes is associated with the loss of telomerase activity without shortening of telomeres. Cell Growth Differ. 9: 85,1998 21. Matsui M, Miyasaka J, Hamada K. Influence of aging and cell senescence on telomerase activity in keratinocytes. J Dermatol Sci. 22: 80,2000 21. Martin IC, Brown AE. Free vascularised fascial flap in oral cavity reconstruction. Head Neck. 16: 45,1994 (Kito K, Kagami H, Kobayashi C, Terasaki H, Miyata Y, Okada K, Fujimoto A, Hata K, Tomita Y, Ito A, Hayashida M, Honda H, Kobayashi T, Sugimura Y, Torii S, Horie K, Hibino Y, Toriyama K, Sumi Y, Mizuno H, Niimi A, Emi N, Abe A, Takahashi I, Kojima T, Saito H, Ueda M) Chapter 2 Cornea Effects of cryopreservation against cultured corneal epithelial cell sheets The recent development of tissue engineering [1, 2] has enabled the clinical application of cultured corneal epithelial cell sheets.
TEOM injection may be able to compensate for the insufficient distraction gap at a higher rate (Fig. 12). Chapter 3: Bone 25 Fig. 11. A: Schematic drawing of the maxilla and maxillary distraction. Red line, osteotomized line; yellow area, maxilla. Fig. 11. B: Distraction protocol and experimental design (From Kinoshita et al. 2008. Reprinted with permission). 0 mm Fig. 12. Histological view of the distracted maxilla, staining H-E. Experimental group A: TEOM-injected side; B: center of the distraction zone on the TEOM-injected side; C: saline solution-injected side; D: center of the distraction zone on the saline solution-injected side.
However, although these treatments have been reported to be effective for periodontal tissue regeneration, the indications for such treatments are rather limited and the amounts of regenerated tissue are not predictable. This indicates that further theoretical and technical developments are needed in the field of periodontal regenerative therapies before such therapy can be widely used in daily practice. In the previous cases, we used injectable tissue-engineered bone grafting to effectively regenerate bone for dental implant placement, and the result confirmed that tissue engineering can elicit as much bone regeneration as autologous bone grafts.
Applied Tissue Engineering by Minoru Ueda (Ed.)