Category: Biomedical Engineering

By Suresh R. Devasahayam

ISBN-10: 1461369290

ISBN-13: 9781461369295

ISBN-10: 1461542995

ISBN-13: 9781461542995

Using electronic sign processing is ubiquitous within the box of body structure and biomedical engineering. the applying of such mathematical and computational instruments calls for a proper or particular realizing of body structure. Formal types and analytical thoughts are interlinked in body structure as in the other box. This booklet takes a unitary method of physiological platforms, starting with sign dimension and acquisition, via sign processing, linear platforms modelling, and computing device simulations. The sign processing ideas variety throughout filtering, spectral research and wavelet research. Emphasis is put on primary realizing of the thoughts in addition to fixing numerical difficulties. Graphs and analogies are used greatly to complement the math. distinctive types of nerve and muscle on the mobile and systemic degrees offer examples for the mathematical tools and desktop simulations. numerous of the versions are sufficiently refined to be of worth in knowing actual international matters like neuromuscular disorder. This moment variation beneficial properties accelerated challenge units and a hyperlink to additional downloadable fabric.

By Dan H. Moore (Eds.)

ISBN-10: 1483167410

ISBN-13: 9781483167411

By Roger Bate

ISBN-10: 0844742643

ISBN-13: 9780844742649

Counterfeit prescription drugs kill millions of individuals each year. even though such a lot pervasive in bad nations, counterfeit drug trafficking is a being concerned new phenomenon within the constructed global. Payoffs for counterfeiters are high--the worldwide marketplace quantities to billions of bucks in line with year--and capability punishment is mild in comparison to the stern consequences dealing with narcotics purchasers. From web pharmacies frequented by means of American shoppers to the again streets of recent Delhi, counterfeit drug trafficking is a fancy, lethal, and more and more profitable that's changing into an enticing enviornment for geared up crime. during this groundbreaking examine, Roger Bate lines pharmaceutical counterfeiting all over the world, from constructed international locations, the place counterfeits usually goal "lifestyle" medicinal drugs equivalent to Viagra, to constructing nations, the place counterfeiters desire healing medicinal drugs resembling antimalarials and antibiotics. Enforcement in constructing international locations is hampered through insufficient schooling, feeble law, and slow policing of present legislation. the us is suffering to thwart an insidious net marketplace. creating a Killing: The lethal Implications of the Counterfeit Drug alternate champions larger cooperation among prosperous and bad international locations to quash the exchange in counterfeit prescribed drugs. Bate demands fortified policing assets, harsher consequences for counterfeiters, frequent public schooling, and common-sense client vigilance by contrast threat. Western policymakers needs to act instantly to quell the lethal counterfeit industry in constructing countries--and to make sure the integrity in their items at domestic.

By Sabine Globig, William Hunter Jr.

ISBN-10: 1466558393

ISBN-13: 9781466558397

Pharmaceutical expertise bargains with the invention, construction, processing, and secure and potent supply of medicines to sufferers. applied sciences concerned comprise machine modeling for learn, bioengineering for learn instrumentation, strategies and strategies for expanding creation, and computing expertise and biosystematics for the administration and research of knowledge. This new e-book covers a variety of vital issues on trendy pharmaceutical expertise, comparable to in vitro drug unlock and regulated drug supply, using nanotechnology in prescribed drugs, quantum dot imaging, asse. Read more...

By Gerhard Swiegers, Jean-Marie Lehn, Janine Benyus

ISBN-10: 0470566671

ISBN-13: 9780470566671

Do we emulate nature's expertise in chemistry?Through billions of years of evolution, Nature has generated a few impressive structures and elements that experience made lifestyles on the earth what it really is this day. more and more, scientists are searching for to imitate Nature's platforms and tactics within the lab with a purpose to harness the facility of Nature for the good thing about society.Bioinspiration and Biomimicry in Chemistry explores the chemistry of Nature and the way we will be able to reflect what Nature does in abiological settings. in particular, the publication specializes in entirely man made, man-made platforms that hire or are encouraged via rules of Nature, yet which don't use fabrics of organic origin.Beginning with a common evaluate of the concept that of bioinspiration and biomimicry in chemistry, the booklet tackles such themes as:Bioinspired molecular machinesBioinspired catalysisBiomimetic amphiphiles and vesiclesBiomimetic rules in macromolecular scienceBiomimetic cavities and bioinspired receptorsBiomimicry in natural synthesisWritten by means of a group of top foreign specialists, the contributed chapters jointly lay the basis for a brand new iteration of environmentally pleasant and sustainable fabrics, prescription drugs, and applied sciences. Readers will realize the newest advances in our skill to duplicate traditional structures and fabrics in addition to the numerous impediments that stay, proving how a lot we nonetheless have to know about how Nature works.Bioinspiration and Biomimicry in Chemistry is suggested for college students and researchers in all geographical regions of chemistry. Addressing how scientists are operating to opposite engineer Nature in all components of chemical learn, the ebook is designed to stimulate new dialogue and study during this interesting and promising field.

Short description
This booklet experiences and summarizes the various and sundry types of bioinspiration and biomimicry which are present in chemistry, from the crude to the hugely refined, from the near-biological to the utterly business and abiological. It severely evaluates our precise figuring out of organic techniques and structures through contemplating our skill to copy them in non-biological settings. learn chemists will locate severe and holistic review of chemical strategies in nature.

From the contents
Foreword xvii
Jean-Marie Lehn

Foreword xix
Janine Benyus

Preface xxiii

Contributors xxv

1. advent: the concept that of Biomimicry and Bioinspiration in Chemistry 1
Timothy W. Hanks and Gerhard F. Swiegers
1.1 what's Biomimicry and Bioinspiration? 1
1.2 Why search thought from, or reflect Biology? 3
1.3 different Monikers: Bioutilization, Bioextraction, Bioderivation, and Bionics 5
1.4 Biomimicry and Sustainability 5
1.5 Biomimicry and Nanostructure 7
1.6 Bioinspiration and Structural Hierarchies 9
1.7 Bioinspiration and Self-Assembly 11
1.8 Bioinspiration and serve as 12
1.9 destiny views: Drawing idea from the complicated procedure that's Nature 13

2. Bioinspired Self-Assembly I: Self-Assembled constructions 17
Leonard F. Lindoy, Christopher Richardson, and Jack ok. Clegg
2.1 creation 17
2.2 Molecular Clefts, tablets, and Cages 19
2.3 Enzyme Mimics and types: the instance of Carbonic Anhydrase 28
2.4 Self-Assembled Liposome-Like platforms 30
2.5 Ion Channel Mimics 32
2.6 Base-Pairing constructions 34
2.7 DNA-RNA constructions 36
2.8 Bioinspired Frameworks 38
2.9 end 41

3. Bioinspired Self-Assembly II: rules of Cooperativity in Bioinspired Self-Assembling structures 47
Gianfranco Ercolani and Luca Schiaffino
3.1 creation 47
3.2 Statistical elements in Self-Assembly 48
3.3 Allosteric Cooperativity 50
3.4 potent Molarity 52
3.5 Chelate Cooperativity 55
3.6 Interannular Cooperativity 60
3.7 balance of an meeting 62
3.8 end 67

4. Bioinspired Molecular Machines 71
Christopher R. Benson, Andrew I. proportion, and Amar H. Flood
4.1 creation 71
4.2 Mechanical results in organic Machines 78
4.3 Theoretical issues: Flashing Ratchets 83
4.4 Sliding Machines 86
4.5 Rotary cars 102
4.6 relocating higher Scale gadgets 104
4.7 strolling Machines 106
4.8 creative Machines 109
4.9 utilizing man made Bioinspired Machines in Biology 111
4.10 standpoint 111
4.11 end 116

5. Bioinspired fabrics Chemistry I: Organic-Inorganic Nanocomposites 121
Pilar Aranda, Francisco M. Fernandes, Bernd Wicklein, Eduardo Ruiz-Hitzky, Jonathan P. Hill, and Katsuhiko Ariga
5.1 creation 121
5.2 Silicate-Based Bionanocomposites as Bioinspired structures 122
5.3 Bionanocomposite Foams 124
5.4 Biomimetic Membranes 126
5.5 Hierarchically Layered Composites 129
5.6 end 133

6. Bioinspired fabrics Chemistry II: Biomineralization as suggestion for fabrics Chemistry 139
Fabio Nudelman and Nico A. J. M. Sommerdijk
6.1 thought from Nature 139
6.2 studying from Nature 144
6.3 utilizing classes from Nature: Synthesis of Biomimetic and Bioinspired fabrics 146
6.4 end 160

7. Bioinspired Catalysis 165
Gerhard F. Swiegers, Jun Chen, and Pawel Wagner
7.1 advent 165
7.2 A basic Description of the Operation of Catalysts 168
7.3 a short background of Our knowing of the Operation of Enzymes 169
7.4 consultant stories of Bioinspired/Biomimetic Catalysts 177
7.5 the connection among Enzymatic Catalysis and Nonbiological Homogeneous and Heterogeneous Catalysis 192
7.6 chosen High-Performance NonBiological Catalysts that make the most Nature's Catalytic ideas 193
7.7 end: The clients for Harnessing Nature's Catalytic rules 203

8. Biomimetic Amphiphiles and Vesicles 209
Sabine Himmelein and Bart Jan Ravoo
8.1 creation 209
8.2 man made Amphiphiles as construction Blocks for Biomimetic Vesicles 210
8.3 Vesicle Fusion caused by means of Molecular acceptance 216
8.4 Stimuli-Responsive form keep watch over of Vesicles 224
8.5 Transmembrane Signaling and Chemical Nanoreactors 231
8.6 towards better Complexity: Vesicles with Subcompartments 239
8.7 end 245

9. Bioinspired Surfaces I: Gecko-Foot Mimetic Adhesion 251
Liangti Qu, Yan Li, and Liming Dai
9.1 The Hierarchical constitution of Gecko toes 251
9.2 beginning of Adhesion in Gecko Setae 252
9.3 Structural standards for artificial Dry Adhesives 253
9.4 Fabrication of artificial Dry Adhesives 254
9.4.1 Polymer-Based Dry Adhesives 254
9.4.2 Carbon-Nanotube-Based Dry Adhesives 278
9.5 Outlook 284

10. Bioinspired Surfaces II: Bioinspired Photonic fabrics 293
Cun Zhu and Zhong-Ze Gu
10.1 Structural colour in Nature: From Phenomena to beginning 293
10.2 Bioinspired Photonic fabrics 296
10.3 end and Outlook 317

11. Biomimetic ideas in Macromolecular technological know-how 323
Wolfgang H. Binder, Marlen Schunack, Florian Herbst, and Bhanuprathap Pulamagatta
11.1 advent 323
11.2 Polymer Synthesis as opposed to Biopolymer Synthesis 325
11.3 Biomimetic Structural beneficial properties in man made Polymers 330
11.4 move in Polymers 343
11.5 Antibody-Like Binding and Enzyme-Like Catalysis in Polymeric Networks 352
11.6 Self-Healing Polymers 355

12. Biomimetic Cavities and Bioinspired Receptors 367
Stephane Le Gac, Ivan Jabin, and Olivia Reinaud
12.1 creation 367
12.2 Mimics of the Michaelis-Menten Complexes of Zinc(II) Enzymes with Polyimidazolyl Calixarene-Based Ligands 368
12.3 Combining a Hydrophobic hollow space and A Tren-Based Unit: layout of Tunable, flexible, yet hugely Selective Receptors 377
12.4 Self-Assembled Cavities 383
12.5 end 391

13. Bioinspired Dendritic Light-Harvesting structures 397
Andrea M. Della Pelle and Sankaran Thayumanavan
13.1 creation 397
13.2 Dendrimer Architectures 399
13.3 digital strategies in Light-Harvesting Dendrimers 403
13.4 Light-Harvesting Dendrimers in fresh power applied sciences 407
13.5 end 413

14. Biomimicry in natural Synthesis 419
Reinhard W. Hoffmann
14.1 advent 419
14.2 Biomimetic Synthesis of usual items 420
14.3 Biomimetic Reactions in natural Synthesis 437
14.4 Biomimetic issues as an reduction in Structural project 447
14.5 Reflections on Biomimicry in natural Synthesis 448

15. end and destiny views: Drawing concept from the complicated approach that's Nature 455
Clyde W. Cady, David M. Robinson, Paul F. Smith, and Gerhard F. Swiegers
15.1 advent: Nature as a posh process 455
15.2 universal good points of advanced structures and the goals of platforms Chemistry 457
15.3 Examples of study in structures Chemistry 460
15.4 end: platforms Chemistry could have Implications in different Fields 468

References 470

Index 473

By Achim Schweikard, Floris Ernst

ISBN-10: 1118562143

ISBN-13: 9781118562147

ISBN-10: 1848213344

ISBN-13: 9781848213340

During this e-book, we current clinical robotics, its evolution during the last 30 years by way of structure, layout and regulate, and the most clinical and medical contributions to the field.
For greater than twenty years, robots were a part of hospitals and feature steadily develop into a standard instrument for the clinician. simply because this area has now reached a undeniable point of adulthood it sort of feels vital and beneficial to supply a kingdom of the medical, technological and medical achievements and nonetheless open issues.
This e-book describes the quick heritage of the area, its specificity and constraints, and mature medical software parts. It additionally provides the foremost techniques by way of layout and keep an eye on together with man-machine interplay modes. a wide cutting-edge is gifted and lots of examples from the literature are integrated and carefully discussed.
It goals to supply either a huge and precis view of this very energetic area in addition to keys to figuring out the evolutions of the area and to arrange for the longer term. An perception to medical assessment is usually proposed, and the publication is done with a bankruptcy on destiny advancements for intra-body robots.Content:
Chapter 1 features and state-of-the-art (pages 1–54): Etienne Dombre, Michel De Mathelin and Jocelyne Troccaz
Chapter 2 clinical Robotics within the provider of the sufferer (pages 55–68): Alexandre Moreau?Gaudry and Philippe Cinquin
Chapter three Inter?operative Sensors and Registration (pages 69–100): Jocelyne Troccaz
Chapter four Augmented truth (pages 101–140): Stephane Nicolau, Luc Soler and Jacques Marescaux
Chapter five layout of clinical Robots (pages 141–176): Etienne Dombre, Philippe Poignet and Francois Pierrot
Chapter 6 Vision?based keep an eye on (pages 177–232): Jacques Gangloff, Florent Nageotte and Philippe Poignet
Chapter 7 interplay Modeling and strength keep watch over (pages 233–268): Philippe Poignet and Bernard Bayle
Chapter eight Tele?manipulation (pages 269–302): Bernard Bayle and Laurent Barbe
Chapter nine Comanipulation (pages 303–350): Guillaume Morel, Jerome Szewczyk and Marie?Aude Vitrani
Chapter 10 in the direction of Intracorporeal Robotics (pages 351–396): Etienne Dombre, Nicolas Chaillet and Michel de Mathelin

By Shaurya Prakash and Junghoon Yeom (Auth.)

ISBN-10: 1437744699

ISBN-13: 9781437744699

To offer an interdisciplinary readership with the required toolkit to paintings with micro- and nanofluidics, this booklet presents simple concept, basics of microfabrication, complex fabrication equipment, equipment characterization tools and distinct examples of functions of nanofluidics units and platforms. Case reviews describing fabrication of advanced micro- and nanoscale platforms support the reader achieve a realistic figuring out of constructing and fabricating such structures. The ensuing paintings covers the basics, techniques and utilized demanding situations of sensible engineered nanofluidic structures for various assorted purposes, together with discussions of lab-on-chip, bio-related functions and rising applied sciences for strength and environmental engineering.

• The basics of micro- and nanofluidic platforms and micro- and nanofabrication recommendations supply readers from various educational backgrounds with the certainty required to advance new structures and applications.
• Case stories introduce and illustrate cutting-edge purposes throughout parts, together with lab-on-chip, power and bio-based applications.
• Prakash and Yeom offer readers with an important toolkit to take micro- and nanofluidic functions out of the learn lab and into advertisement and laboratory applications.

By C. Alexandru

ISBN-10: 9535100122

ISBN-13: 9789535100126

This ebook presents an open platform to set up and proportion wisdom built by way of students, scientists, and engineers from around the globe, approximately a variety of purposes of the modeling and simulation within the layout strategy of items, in a variety of engineering fields. The publication involves 12 chapters prepared in sections (3D Modeling and digital Prototyping), reflecting the multidimensionality of functions relating to modeling and simulation. essentially the most contemporary modeling and simulation innovations, in addition to probably the most exact and complex software program in treating complicated platforms, are utilized.

By Domitilla Del Vecchio, Richard M. Murray

ISBN-10: 0691161534

ISBN-13: 9780691161532

This e-book presents an obtainable advent to the rules and instruments for modeling, studying, and synthesizing biomolecular structures. It starts off with modeling instruments corresponding to reaction-rate equations, reduced-order types, stochastic types, and particular versions of significant center methods. It then describes intimately the keep watch over and dynamical platforms instruments used to research those versions. those comprise instruments for reading balance of equilibria, restrict cycles, robustness, and parameter uncertainty. Modeling and research suggestions are then utilized to layout examples from either normal platforms and artificial biomolecular circuits. additionally, this accomplished ebook addresses the matter of modular composition of man-made circuits, the instruments for examining the level of modularity, and the layout options for making sure modular habit. It additionally appears at layout trade-offs, targeting perturbations as a result of noise and festival for shared mobile resources.

Featuring quite a few workouts and illustrations all through, Biomolecular suggestions Systems is the proper textbook for complicated undergraduates and graduate scholars. For researchers, it will probably additionally function a self-contained reference at the suggestions keep watch over options that may be utilized to biomolecular systems.

• Provides a simple creation to crucial suggestions, instruments, and applications
• Covers the main standard modeling methods
• Addresses the modular layout challenge for biomolecular systems
• Uses layout examples from either normal structures and artificial circuits
• Solutions guide (available in simple terms to professors at press,princeton.edu)
• An on-line representation package deal is on the market to professors at press.princeton.edu

By Werner Nachtigall, Alfred Wisser

ISBN-10: 3319058576

ISBN-13: 9783319058573

ISBN-10: 3319058584

ISBN-13: 9783319058580

Bionics potential studying from the character for the advance of know-how. The technology of "bionics" itself is classed into numerous sections, from fabrics and constructions over techniques and techniques till evolution and optimization. now not these kinds of components, or just a couple of, are particularly identified within the public and likewise in clinical literature. This comprises the Lotus-effect, switched over to the contamination-reduction of fassades and the shark-shed-effect, switched over to the resistance-reduction of airplanes. besides the fact that, there are countless numbers of hugely fascinating examples that include the transformation of rules of the character into expertise. From the big variety of those examples, 250 have been chosen for the current e-book in accordance with "prehistory", "early-history", "classic" and "modern time". such a lot examples are new. each instance features a published web page in a homogeneous association. The examples from the sector "modern time" are joint in blocks resembling the sub-disciplines of bionics.