By Arnaud Chauvière, Luigi Preziosi, Claude Verdier
Ubiquitous and primary in phone mechanics, multiscale difficulties can come up within the development of tumors, embryogenesis, tissue engineering, and extra. Cell Mechanics: From unmarried Scale-Based versions to Multiscale Modeling brings jointly new perception and study on mechanical, mathematical, actual, and organic techniques for simulating the habit of cells, particularly tumor cells.
In the 1st a part of the textual content, the ebook discusses the robust software of microrheology for investigating phone mechanical houses, multiphysics and multiscale methods for learning intracellular mechanisms in mobilephone motility, and the function of subcellular results concerning definite genes for inducing mobile motility in melanoma. concentrating on versions in accordance with actual, mathematical, and computational ways, the second one part develops instruments for describing the advanced interaction of mobile adhesion molecules and the dynamic evolution of the phone cytoskeleton. The 3rd half explores phone interactions with the surroundings, fairly the position of exterior mechanical forces and their results on mobile habit. the ultimate half provides cutting edge types of multicellular platforms for developmental biology, melanoma, and embryogenesis.
This booklet collects novel easy methods to follow to cells and tissues via a multiscale strategy. It provides quite a few present instruments whereas stimulating the invention of latest methods which could result in more desirable and exact predictions of pathologies.
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Additional resources for Cell Mechanics: From Single Scale-Based Models to Multiscale Modeling (Chapman & Hall CRC Mathematical & Computational Biology)
Time scale dependent viscoelastic and contractile regimes in ﬁbroblasts probed by microplate manipulation. J. Cell Sci. 110:2109–2116.  X. Trepat, M. Grabulosa, L. Buscemi, F. Rico, R. Farr´e, and D. Navajas (2005). Thrombin and histamine induce stiﬀening of alveolar epithelial cells. J. Appl. Physiol. 98:1567–1574. W. Tschoegl (1989). The Phenomenological Theory of Linear Viscoelastic Behavior, Springer, Berlin.  Y. P. Kole, and D. Wirtz (2002). Micromechanical mapping of live cells by multiple-particle-tracking microrheology.
2 Quantitative Model for Velocity Oscillations in Actin-Based Motility . . . . . . . . . . . . . . . 2 Macroscopic Models . . . . . . . . . . . . . . . . . . . . . . 1 Phenomenological Model of Symmetry Breaking . . 2 Role of Tensile Stress during Symmetry Breaking in Actin Gels . . . . . . . . . . . . . . . . . . . . . 3 Nonlinear Study on Symmetry Breaking in Actin Gels . . . . . . .
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Cell Mechanics: From Single Scale-Based Models to Multiscale Modeling (Chapman & Hall CRC Mathematical & Computational Biology) by Arnaud Chauvière, Luigi Preziosi, Claude Verdier